Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM51774
Substrate
n/a
Meas. Tech.
Fluorescent assay for identification of compounds that inhibit VHR1
IC50
3380±n/a nM
Citation
 PubChem, PC Fluorescent assay for identification of compounds that inhibit VHR1 PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM51774
Synonyms:
1'-({[4-(aminosulfonyl)phenyl]amino}carbonothioyl)-1,4'-bipiperidine-4'-carboxamide | 4-(1-piperidinyl)-1-[(4-sulfamoylanilino)-sulfanylidenemethyl]-4-piperidinecarboxamide | 4-piperidin-1-yl-1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-4-carboxamide | 4-piperidino-1-[(4-sulfamoylphenyl)thiocarbamoyl]isonipecotamide | MLS000621463 | SMR000299565 | cid_2193503
Type:
Small organic molecule
Emp. Form.:
C18H27N5O3S2
Mol. Mass.:
425.569
SMILES:
NC(=O)C1(CCN(CC1)C(=S)Nc1ccc(cc1)S(N)(=O)=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: