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Target
Dual specificity protein phosphatase 3
Ligand
BDBM51784
Substrate
n/a
Meas. Tech.
Fluorescent assay for identification of compounds that inhibit VHR1
IC50
11300±n/a nM
Citation
 PubChem, PC Fluorescent assay for identification of compounds that inhibit VHR1 PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM51784
Synonyms:
3-[3-(4-bromophenyl)-5,9-dimethyl-7-oxidanylidene-furo[3,2-g]chromen-6-yl]propanoic acid | 3-[3-(4-bromophenyl)-5,9-dimethyl-7-oxo-6-furo[3,2-g][1]benzopyranyl]propanoic acid | 3-[3-(4-bromophenyl)-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl]propanoic acid | 3-[3-(4-bromophenyl)-7-keto-5,9-dimethyl-furo[3,2-g]chromen-6-yl]propionic acid | MLS001165400 | SMR000540074 | US20230364057, Compound 48 | cid_1960944
Type:
Small organic molecule
Emp. Form.:
C22H17BrO5
Mol. Mass.:
441.271
SMILES:
Cc1c(CCC(O)=O)c(=O)oc2c(C)c3occ(-c4ccc(Br)cc4)c3cc12
Structure:
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