Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM51944
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
49599±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51944
Synonyms:
3-phenyl-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-3-phenyl-1H-1,2,4-triazole-5-thione | MLS000036378 | SMR000059245 | cid_660524
Type:
Small organic molecule
Emp. Form.:
C15H13N3S
Mol. Mass.:
267.349
SMILES:
S=c1[nH]nc(-c2ccccc2)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: