Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM51954
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
12922±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51954
Synonyms:
(2-benzoyl-1H-pyrrol-1-yl)acetic acid | 2-(2-benzoyl-1-pyrrolyl)acetic acid | 2-(2-benzoylpyrrol-1-yl)acetic acid | 2-[2-(phenylcarbonyl)pyrrol-1-yl]ethanoic acid | CHEMBL335619 | MLS000095834 | SMR000031382 | cid_3239785
Type:
Small organic molecule
Emp. Form.:
C13H11NO3
Mol. Mass.:
229.2313
SMILES:
OC(=O)Cn1cccc1C(=O)c1ccccc1
Structure:
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