Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM51965
Substrate
n/a
Meas. Tech.
Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase
IC50
14379±n/a nM
Citation
 PubChem, PC Epi-absorbance-based dose response biochemical high throughput screening assay for selective inhibitors of VIM-2 metallo-beta-lactamase PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51965
Synonyms:
3-(2-furanyl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione | 3-(2-furyl)-4-isobutyl-1H-1,2,4-triazole-5-thione | 3-(furan-2-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione | MLS000565615 | SMR000152755 | cid_843761
Type:
Small organic molecule
Emp. Form.:
C10H13N3OS
Mol. Mass.:
223.295
SMILES:
CC(C)Cn1c(n[nH]c1=S)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: