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Target
Beta-lactamase
Ligand
BDBM51945
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
3514±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51945
Synonyms:
3-(2-furanyl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | 3-(furan-2-yl)-4-(phenylmethyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-3-(2-furyl)-1H-1,2,4-triazole-5-thione | 4-benzyl-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione | MLS000028282 | SMR000059258 | cid_660619
Type:
Small organic molecule
Emp. Form.:
C13H11N3OS
Mol. Mass.:
257.311
SMILES:
S=c1[nH]nc(-c2ccco2)n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: