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Target
Beta-lactamase
Ligand
BDBM51955
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
4154±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51955
Synonyms:
3-phenyl-4-(tetrahydrofurfuryl)-1H-1,2,4-triazole-5-thione | 4-(2-oxolanylmethyl)-3-phenyl-1H-1,2,4-triazole-5-thione | 4-(oxolan-2-ylmethyl)-3-phenyl-1H-1,2,4-triazole-5-thione | 5-phenyl-4-(tetrahydro-2-furanylmethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione | MLS000052645 | SMR000082315 | cid_2981009
Type:
Small organic molecule
Emp. Form.:
C13H15N3OS
Mol. Mass.:
261.343
SMILES:
S=c1[nH]nc(-c2ccccc2)n1CC1CCCO1
Structure:
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