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Target
Beta-lactamase
Ligand
BDBM51688
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
2131±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51688
Synonyms:
(3-Methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)-acetic acid [1-(2,5-dimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide | MLS000555855 | N-[(2,5-dimethoxybenzylidene)amino]-2-(3-keto-5-methyl-2-pyrazolin-4-yl)acetamide | N-[(2,5-dimethoxyphenyl)methylideneamino]-2-(3-methyl-5-oxidanylidene-1,4-dihydropyrazol-4-yl)ethanamide | N-[(2,5-dimethoxyphenyl)methylideneamino]-2-(3-methyl-5-oxo-1,4-dihydropyrazol-4-yl)acetamide | SMR000147372 | cid_3795446
Type:
Small organic molecule
Emp. Form.:
C15H18N4O4
Mol. Mass.:
318.3278
SMILES:
COc1ccc(OC)c(C=NNC(=O)Cc2c(C)[nH][nH]c2=O)c1 |w:10.10|
Structure:
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