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Target
Beta-lactamase
Ligand
BDBM51989
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
774±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51989
Synonyms:
3-[3-(2,4-dichlorobenzyl)oxy-2-thienyl]-4-methyl-1H-1,2,4-triazole-5-thione | 3-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-4-methyl-1H-1,2,4-triazole-5-thione | 3-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-4-methyl-1H-1,2,4-triazole-5-thione | 5-{3-[(2,4-dichlorobenzyl)oxy]-2-thienyl}-4-methyl-4H-1,2,4-triazole-3-thiol | MLS000692151 | SMR000333829 | cid_1482500
Type:
Small organic molecule
Emp. Form.:
C14H11Cl2N3OS2
Mol. Mass.:
372.293
SMILES:
Cn1c(n[nH]c1=S)-c1sccc1OCc1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: