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Target
Beta-lactamase
Ligand
BDBM52016
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
9800±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM52016
Synonyms:
4-(4-Chloro-benzylamino)-2-oxo-1,2-dihydro-quinoline-3-carbaldehyde | 4-[(4-chlorobenzyl)amino]-2-keto-1H-quinoline-3-carbaldehyde | 4-[(4-chlorophenyl)methylamino]-2-oxidanylidene-1H-quinoline-3-carbaldehyde | 4-[(4-chlorophenyl)methylamino]-2-oxo-1H-quinoline-3-carbaldehyde | 4-[(4-chlorophenyl)methylamino]-2-oxo-1H-quinoline-3-carboxaldehyde | MLS001208523 | SMR000504538 | cid_6502653
Type:
Small organic molecule
Emp. Form.:
C17H13ClN2O2
Mol. Mass.:
312.75
SMILES:
Clc1ccc(CNc2c(C=O)c(=O)[nH]c3ccccc23)cc1
Structure:
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