Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52244
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
46579±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52244
Synonyms:
1-(4-chlorophenyl)-4-oxidanylidene-7-phenyl-3-(phenylmethyl)pyrimido[1,2-b]pyridazin-5-ium-2-olate | 1-(4-chlorophenyl)-4-oxo-7-phenyl-3-(phenylmethyl)-2-pyrimido[1,2-b]pyridazin-5-iumolate | 3-benzyl-1-(4-chlorophenyl)-4-keto-7-phenyl-pyrimido[1,2-b]pyridazin-5-ium-2-olate | 3-benzyl-1-(4-chlorophenyl)-4-oxo-7-phenyl-4H-pyrimido[1,2-b]pyridazin-1-ium-2-olate | 3-benzyl-1-(4-chlorophenyl)-4-oxo-7-phenylpyrimido[1,2-b]pyridazin-5-ium-2-olate | MLS000594496 | SMR000113828 | cid_3518713
Type:
Small organic molecule
Emp. Form.:
C26H18ClN3O2
Mol. Mass.:
439.893
SMILES:
[O-]c1c(Cc2ccccc2)c(=O)n(-c2ccc(Cl)cc2)c2ccc(n[n+]12)-c1ccccc1
Structure:
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