Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52249
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52249
Synonyms:
(5E)-1-benzyl-5-[[4-(diethylamino)anilino]methylene]barbituric acid | (5E)-1-benzyl-5-[[4-(diethylamino)anilino]methylidene]-1,3-diazinane-2,4,6-trione | (5E)-5-[[4-(diethylamino)anilino]methylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | (5E)-5-[[[4-(diethylamino)phenyl]amino]methylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | (5Z)-1-benzyl-5-[[4-(diethylamino)anilino]methylene]barbituric acid | 1-Benzyl-5-[1-(4-diethylamino-phenylamino)-meth-(E)-ylidene]-pyrimidine-2,4,6-trione | MLS000555566 | SMR000147283 | cid_5520426
Type:
Small organic molecule
Emp. Form.:
C22H24N4O3
Mol. Mass.:
392.451
SMILES:
CCN(CC)c1ccc(NC=C2C(=O)NC(=O)N(Cc3ccccc3)C2=O)cc1 |w:10.9|
Structure:
Search PDB for entries with ligand similarity: