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Target
Zinc finger protein mex-5
Ligand
BDBM52295
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52295
Synonyms:
(5E)-1-(4-chlorophenyl)-5-[1-(2-piperidin-1-ylethylamino)ethylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(4-chlorophenyl)-5-[1-(2-piperidinoethylamino)ethylidene]barbituric acid | (5E)-1-(4-chlorophenyl)-5-[1-[2-(1-piperidinyl)ethylamino]ethylidene]-1,3-diazinane-2,4,6-trione | 1-(4-Chloro-phenyl)-5-[1-(2-piperidin-1-yl-ethylamino)-eth-(E)-ylidene]-pyrimidine-2,4,6-trione | MLS000558583 | SMR000149099 | cid_6230943
Type:
Small organic molecule
Emp. Form.:
C19H23ClN4O3
Mol. Mass.:
390.864
SMILES:
CC(=NCCN1CCCCC1)c1c(O)n(-c2ccc(Cl)cc2)c(=O)[nH]c1=O |w:2.2|
Structure:
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