Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52300
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52300
Synonyms:
2-[3-methyl-5-(2-methylpropyl)-1-pyrazolyl]-3-phenylmethoxy-4-quinazolinone | 2-[3-methyl-5-(2-methylpropyl)pyrazol-1-yl]-3-phenylmethoxy-quinazolin-4-one | 2-[3-methyl-5-(2-methylpropyl)pyrazol-1-yl]-3-phenylmethoxyquinazolin-4-one | 3-Benzyloxy-2-(5-isobutyl-3-methyl-pyrazol-1-yl)-3H-quinazolin-4-one | 3-benzoxy-2-(5-isobutyl-3-methyl-pyrazol-1-yl)quinazolin-4-one | MLS000558206 | SMR000148922 | cid_2023456
Type:
Small organic molecule
Emp. Form.:
C23H24N4O2
Mol. Mass.:
388.4623
SMILES:
CC(C)Cc1cc(C)nn1-c1nc2ccccc2c(=O)n1OCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: