Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM50776
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
27026±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM50776
Synonyms:
6-chloranyl-3-methyl-1H-imidazo[4,5-b]pyridin-2-one | 6-chloro-3-methyl-1H-imidazo[4,5-b]pyridin-2-one | MLS000079417 | SMR000038782 | cid_657849
Type:
Small organic molecule
Emp. Form.:
C7H6ClN3O
Mol. Mass.:
183.595
SMILES:
Cn1c2ncc(Cl)cc2[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: