Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52177
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52177
Synonyms:
2-[(2-chlorophenyl)amino]-2-oxoethyl 3-(2-oxo-2,3-dihydro-1H-imidazol-4-yl)propanoate | 3-(2-keto-4-imidazolin-4-yl)propionic acid [2-(2-chloroanilino)-2-keto-ethyl] ester | 3-(2-oxo-1,3-dihydroimidazol-4-yl)propanoic acid [2-(2-chloroanilino)-2-oxoethyl] ester | MLS000088097 | SMR000072320 | [2-(2-chloroanilino)-2-oxoethyl] 3-(2-oxo-1,3-dihydroimidazol-4-yl)propanoate | [2-[(2-chlorophenyl)amino]-2-oxidanylidene-ethyl] 3-(2-oxidanylidene-1,3-dihydroimidazol-4-yl)propanoate | cid_889213
Type:
Small organic molecule
Emp. Form.:
C14H14ClN3O4
Mol. Mass.:
323.732
SMILES:
Clc1ccccc1NC(=O)COC(=O)CCc1c[nH]c(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: