Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 6
Ligand
BDBM53486
Substrate
n/a
Meas. Tech.
MKP-3 in vitro HTS assay
IC50
100000±n/a nM
Citation
 PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM53486
Synonyms:
4-(phenylmethyl)-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester | 4-Benzyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | 4-benzylthieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester | MLS000068097 | SMR000007154 | cid_649131 | ethyl 4-(phenylmethyl)thieno[3,2-b]pyrrole-5-carboxylate | ethyl 4-benzylthieno[3,2-b]pyrrole-5-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H15NO2S
Mol. Mass.:
285.361
SMILES:
CCOC(=O)c1cc2sccc2n1Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: