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Target
Dual specificity protein phosphatase 6
Ligand
BDBM40576
Substrate
n/a
Meas. Tech.
MKP-3 in vitro HTS assay
IC50
10000±n/a nM
Citation
 PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM40576
Synonyms:
2-(2,5-Dimethyl-pyrrol-1-yl)-3-phenyl-propionic acid | 2-(2,5-dimethyl-1-pyrrolyl)-3-phenylpropanoic acid | 2-(2,5-dimethylpyrrol-1-yl)-3-phenyl-propanoic acid | 2-(2,5-dimethylpyrrol-1-yl)-3-phenyl-propionic acid | 2-(2,5-dimethylpyrrol-1-yl)-3-phenylpropanoic acid | MLS000072791 | SMR000010168 | cid_654761
Type:
Small organic molecule
Emp. Form.:
C15H17NO2
Mol. Mass.:
243.301
SMILES:
Cc1ccc(C)n1C(Cc1ccccc1)C(O)=O
Structure:
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