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Target
Dual specificity protein phosphatase 6
Ligand
BDBM43865
Substrate
n/a
Meas. Tech.
MKP-3 in vitro HTS assay
IC50
48200±n/a nM
Citation
 PubChem, PC MKP-3 in vitro HTS assay PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 6
Synonyms:
DUS6_RAT | Dusp6 | MAP kinase phosphatase 3 | MKP-3 | Mitogen-activated protein kinase phosphatase 3 | Mkp3
Type:
Enzyme
Mol. Mass.:
42303.19
Organism:
Rattus norvegicus
Description:
gi_16758752
Residue:
381
Sequence:
MIDTLRPVPFASEMAISKTVAWLNEQLELGNEQLLLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRCEDRDRFTRRCGTDTVVLYDENSSDWNENTGGESVLGLLLKKLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQLYFTAPSNQNVYQVDSLQST
  
Inhibitor
Name:
BDBM43865
Synonyms:
6-formyl-4,7-dihydroxy-9-keto-5H-phenazine-1-carboxylic acid methyl ester | 6-formyl-4,7-dihydroxy-9-oxo-5H-phenazine-1-carboxylic acid methyl ester | Glycopeptide, 4 | Lomofungin | MLS000766240 | SMR000528852 | cid_5351222 | methyl 6-formyl-4,7-dihydroxy-9-oxo-5H-phenazine-1-carboxylate | methyl 6-methanoyl-4,7-bis(oxidanyl)-9-oxidanylidene-5H-phenazine-1-carboxylate
Type:
Peptide
Emp. Form.:
C15H10N2O6
Mol. Mass.:
314.2497
SMILES:
COC(=O)c1ccc(O)c2nc3c(C=O)c(O)cc(O)c3nc12
Structure:
Search PDB for entries with ligand similarity: