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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM41228
Substrate
n/a
Meas. Tech.
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50
1140±n/a nM
Citation
 PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM41228
Synonyms:
2,3,5,6-tetrakis(2-furanyl)pyrazine | 2,3,5,6-tetrakis(2-furyl)pyrazine | 2,3,5,6-tetrakis(furan-2-yl)pyrazine | MLS000055488 | SMR000065994 | cid_854635
Type:
Small organic molecule
Emp. Form.:
C20H12N2O4
Mol. Mass.:
344.3203
SMILES:
c1coc(c1)-c1nc(-c2ccco2)c(nc1-c1ccco1)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: