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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM53562
Substrate
n/a
Meas. Tech.
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50
100000±n/a nM
Citation
 PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM53562
Synonyms:
(7-chloro-4-quinolinyl)[2-(diethylamino)ethyl]amine | 2-[(7-chloro-4-quinolyl)amino]ethyl-diethyl-amine | MLS000066547 | N-(7-chloranylquinolin-4-yl)-N',N'-diethyl-ethane-1,2-diamine | N-(7-chloro-4-quinolinyl)-N',N'-diethylethane-1,2-diamine | N-(7-chloroquinolin-4-yl)-N',N'-diethylethane-1,2-diamine | SMR000080960 | cid_408190
Type:
Small organic molecule
Emp. Form.:
C15H20ClN3
Mol. Mass.:
277.792
SMILES:
CCN(CC)CCNc1ccnc2cc(Cl)ccc12
Structure:
Search PDB for entries with ligand similarity: