Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM53572
Substrate
n/a
Meas. Tech.
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50
100000±n/a nM
Citation
 PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM53572
Synonyms:
MLS000118423 | N-(4-fluorobenzyl)pyrazolo[1,5-a]pyridine-2-carboxamide | N-[(4-fluorophenyl)methyl]-2-pyrazolo[1,5-a]pyridinecarboxamide | N-[(4-fluorophenyl)methyl]pyrazolo[1,5-a]pyridine-2-carboxamide | SMR000095364 | cid_5308800
Type:
Small organic molecule
Emp. Form.:
C15H12FN3O
Mol. Mass.:
269.2737
SMILES:
Fc1ccc(CNC(=O)c2cc3ccccn3n2)cc1
Structure:
Search PDB for entries with ligand similarity: