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Target
Mannose-6-phosphate isomerase
Ligand
BDBM53589
Substrate
n/a
Meas. Tech.
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
50000±n/a nM
Citation
 PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2009)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM53589
Synonyms:
3-hydroxy-N-(2-hydroxyethyl)-2-naphthalenecarboxamide | 3-hydroxy-N-(2-hydroxyethyl)-2-naphthamide | 3-hydroxy-N-(2-hydroxyethyl)naphthalene-2-carboxamide | MLS000061208 | N-(2-hydroxyethyl)-3-oxidanyl-naphthalene-2-carboxamide | SMR000069276 | cid_66722
Type:
Small organic molecule
Emp. Form.:
C13H13NO3
Mol. Mass.:
231.2472
SMILES:
OCCNC(=O)c1cc2ccccc2cc1O
Structure:
Search PDB for entries with ligand similarity: