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Target
Mannose-6-phosphate isomerase
Ligand
BDBM53619
Substrate
n/a
Meas. Tech.
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
50000±n/a nM
Citation
 PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2009)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM53619
Synonyms:
MLS000710661 | N-(3-ethyl-2-methyl-1-phenyl-5-benzimidazol-3-iumyl)acetamide;iodide | N-(3-ethyl-2-methyl-1-phenyl-benzimidazol-3-ium-5-yl)acetamide;iodide | N-(3-ethyl-2-methyl-1-phenyl-benzimidazol-3-ium-5-yl)ethanamide;iodide | N-(3-ethyl-2-methyl-1-phenylbenzimidazol-3-ium-5-yl)acetamide;iodide | SMR000280428 | cid_16189423
Type:
Small organic molecule
Emp. Form.:
C18H20N3O
Mol. Mass.:
294.3704
SMILES:
CCn1c(C)[n+](-c2ccccc2)c2ccc(NC(C)=O)cc12
Structure:
Search PDB for entries with ligand similarity: