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Target
M1 family aminopeptidase
Ligand
BDBM53869
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP)
IC50
1000±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) PubChem Bioassay (2008)[AID] 
Target
Name:
M1 family aminopeptidase
Synonyms:
AMPN_PLAF7 | M1AAP | Zinc aminopeptidase | m1-family aminopeptidase
Type:
PROTEIN
Mol. Mass.:
126072.31
Organism:
Plasmodium falciparum (isolate FcB1 / Columbia)
Description:
ChEMBL_735637
Residue:
1085
Sequence:
MKLTKGCAYKYIIFTVLILANILYDNKKRCMIKKNLRISSCGIISRLLKSNSNYNSFNKNYNFTSAISELQFSNFWNLDILQKDIFSNIHNNKNKPQSYIIHKRLMSEKGDNNNNNHQNNNGNDNKKRLGSVVNNEENTCSDKRMKPFEEGHGITQVDKMNNNSDHLQQNGVMNLNSNNVENNNNNNSVVVKKNEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
  
Inhibitor
Name:
BDBM53869
Synonyms:
(4-{[(2-[(2,6-dimethylphenoxy)methyl]-4-oxo-3(4H)-quinazolinyl)imino]methyl}phenoxy)acetic acid | 2-[4-[[2-[(2,6-dimethylphenoxy)methyl]-4-keto-quinazolin-3-yl]iminomethyl]phenoxy]acetic acid | 2-[4-[[2-[(2,6-dimethylphenoxy)methyl]-4-oxidanylidene-quinazolin-3-yl]iminomethyl]phenoxy]ethanoic acid | 2-[4-[[2-[(2,6-dimethylphenoxy)methyl]-4-oxo-3-quinazolinyl]iminomethyl]phenoxy]acetic acid | 2-[4-[[2-[(2,6-dimethylphenoxy)methyl]-4-oxoquinazolin-3-yl]iminomethyl]phenoxy]acetic acid | MLS000705463 | SMR000230514 | cid_1042981
Type:
Small organic molecule
Emp. Form.:
C26H23N3O5
Mol. Mass.:
457.4779
SMILES:
Cc1cccc(C)c1OCc1nc2ccccc2c(=O)n1N=Cc1ccc(OCC(O)=O)cc1
Structure:
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