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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM61197
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
680±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM61197
Synonyms:
(2,6-dipyrrolidinopyrimidin-4-yl)-(p-anisylideneamino)amine | 4-methoxybenzaldehyde (2,6-dipyrrolidin-1-ylpyrimidin-4-yl)hydrazone | MLS000720213 | N-[(4-methoxyphenyl)methylideneamino]-2,6-bis(1-pyrrolidinyl)-4-pyrimidinamine | N-[(4-methoxyphenyl)methylideneamino]-2,6-dipyrrolidin-1-yl-pyrimidin-4-amine | N-[(4-methoxyphenyl)methylideneamino]-2,6-dipyrrolidin-1-ylpyrimidin-4-amine | SMR000304742 | cid_2851352
Type:
Small organic molecule
Emp. Form.:
C20H26N6O
Mol. Mass.:
366.46
SMILES:
COc1ccc(CN=Nc2cc(nc(n2)N2CCCC2)N2CCCC2)cc1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: