Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54703
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested by Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54703
Synonyms:
1-(4-methoxyphenyl)-3-phenyl-2-propyn-1-one | 1-(4-methoxyphenyl)-3-phenyl-prop-2-yn-1-one | 1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-one | UNM-0000306061 | cid_616715
Type:
Small organic molecule
Emp. Form.:
C16H12O2
Mol. Mass.:
236.2653
SMILES:
COc1ccc(cc1)C(=O)C#Cc1ccccc1
Structure:
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