Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54700
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54700
Synonyms:
3-phenyl-1-[4-(trifluoromethoxy)phenyl]-2-propyn-1-one | 3-phenyl-1-[4-(trifluoromethoxy)phenyl]prop-2-yn-1-one | 3-phenyl-1-[4-(trifluoromethyloxy)phenyl]prop-2-yn-1-one | UNM-0000306058 | cid_25109936
Type:
Small organic molecule
Emp. Form.:
C16H9F3O2
Mol. Mass.:
290.2367
SMILES:
FC(F)(F)Oc1ccc(cc1)C(=O)C#Cc1ccccc1
Structure:
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