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Target
GTPase KRas [1-37]
Ligand
BDBM54676
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54676
Synonyms:
(3Z)-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)oxindole | (3Z)-3-(5-oxidanylidene-2-sulfanylidene-imidazolidin-4-ylidene)-1H-indol-2-one | (3Z)-3-(5-oxo-2-sulfanylidene-4-imidazolidinylidene)-1H-indol-2-one | (3Z)-3-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)-1H-indol-2-one | UNM-0000305762 | cid_5339891
Type:
Small organic molecule
Emp. Form.:
C11H7N3O2S
Mol. Mass.:
245.257
SMILES:
O=C1NC(=S)N\C1=C1/C(=O)Nc2ccccc12
Structure:
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