Target
GTPase KRas [1-37]
Ligand
BDBM54679
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54679
Synonyms:
(3E)-4-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylidene)-1H-indol-2-one | (3E)-4-bromo-3-(1-ketoindan-2-ylidene)oxindole | (3E)-4-bromo-3-(3-oxo-1H-inden-2-ylidene)-1H-indol-2-one | UNM-0000305765 | cid_25220926
Type:
Small organic molecule
Emp. Form.:
C17H10BrNO2
Mol. Mass.:
340.171
SMILES:
Brc1cccc2NC(=O)\C(=C3/Cc4ccccc4C3=O)c12
Structure:
Search PDB for entries with ligand similarity: