Reaction Details Report a problem with these data
Target
GTPase KRas [1-37]
Ligand
BDBM54683
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54683
Synonyms:
7-fluoranyl-3-[3-(oxidanylamino)-1H-indol-2-yl]indol-2-one | 7-fluoro-3-[3-(hydroxyamino)-1H-indol-2-yl]-2-indolone | 7-fluoro-3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one | UNM-0000305773 | cid_11845975
Type:
Small organic molecule
Emp. Form.:
C16H10FN3O2
Mol. Mass.:
295.2679
SMILES:
ONc1c([nH]c2ccccc12)C1=c2cccc(F)c2=NC1=O |c:13,21|
Structure:
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