Reaction Details Report a problem with these data
Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54677
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54677
Synonyms:
(3E)-3-(1-ketoindan-2-ylidene)oxindole | (3E)-3-(3-oxidanylidene-1H-inden-2-ylidene)-1H-indol-2-one | (3E)-3-(3-oxo-1H-inden-2-ylidene)-1H-indol-2-one | UNM-0000305763 | cid_25220924
Type:
Small organic molecule
Emp. Form.:
C17H11NO2
Mol. Mass.:
261.2747
SMILES:
O=C1Nc2ccccc2\C1=C1\Cc2ccccc2C1=O
Structure:
Search PDB for entries with ligand similarity: