Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54704
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54704
Synonyms:
UNM-0000306098 | cid_23681059 | sodium;(2S)-2-(6-methoxy-2-naphthalenyl)propanoate | sodium;(2S)-2-(6-methoxy-2-naphthyl)propionate | sodium;(2S)-2-(6-methoxynaphthalen-2-yl)propanoate
Type:
Small organic molecule
Emp. Form.:
C14H13O3
Mol. Mass.:
229.2518
SMILES:
COc1ccc2cc(ccc2c1)[C@H](C)C([O-])=O
Structure:
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