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Target
GTPase KRas [1-37]
Ligand
BDBM54698
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
EC50
30000±n/a nM
Comments
Extracted from aid = 2043 and tid = 2
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54698
Synonyms:
3-phenyl-1-(3-pyridinyl)-2-propyn-1-one | 3-phenyl-1-(3-pyridyl)prop-2-yn-1-one | 3-phenyl-1-pyridin-3-yl-prop-2-yn-1-one | 3-phenyl-1-pyridin-3-ylprop-2-yn-1-one | UNM-0000306056 | cid_326117
Type:
Small organic molecule
Emp. Form.:
C14H9NO
Mol. Mass.:
207.2274
SMILES:
O=C(C#Cc1ccccc1)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: