Target
GTPase KRas [1-37]
Ligand
BDBM54701
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
EC50
18155±n/a nM
Comments
Extracted from aid = 2043 and tid = 2
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54701
Synonyms:
1-(4-fluorophenyl)-3-phenyl-2-propyn-1-one | 1-(4-fluorophenyl)-3-phenyl-prop-2-yn-1-one | 1-(4-fluorophenyl)-3-phenylprop-2-yn-1-one | UNM-0000306059 | cid_13200052
Type:
Small organic molecule
Emp. Form.:
C15H9FO
Mol. Mass.:
224.2298
SMILES:
Fc1ccc(cc1)C(=O)C#Cc1ccccc1
Structure:
Search PDB for entries with ligand similarity: