Target
Ras-related protein Rab-2A
Ligand
BDBM54627
Substrate
n/a
Meas. Tech.
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
30000±n/a nM
Comments
Extracted from aid = 2045 and tid = 2
Citation
 PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2016)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54627
Synonyms:
4-[5-(4-fluorophenyl)-2-phenyl-3,4-dihydropyrazol-3-yl]-N,N-dimethyl-aniline | 4-[5-(4-fluorophenyl)-2-phenyl-3,4-dihydropyrazol-3-yl]-N,N-dimethylaniline | UNM-0000305866 | [4-[5-(4-fluorophenyl)-2-phenyl-2-pyrazolin-3-yl]phenyl]-dimethyl-amine | cid_2932251
Type:
Small organic molecule
Emp. Form.:
C23H22FN3
Mol. Mass.:
359.4393
SMILES:
CN(C)c1ccc(cc1)C1CC(=NN1c1ccccc1)c1ccc(F)cc1 |c:12|
Structure:
Search PDB for entries with ligand similarity: