Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54702
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
30000±n/a nM
Citation
PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID]
More Info.:
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
Inhibitor
Name:
BDBM54702
Synonyms:
4-(1-oxo-3-phenylprop-2-ynyl)benzoic acid methyl ester | 4-(3-phenylpropioloyl)benzoic acid methyl ester | UNM-0000306060 | cid_15568606 | methyl 4-(3-phenylprop-2-ynoyl)benzoate
Type:
Small organic molecule
Emp. Form.:
C17H12O3
Mol. Mass.:
264.2754
SMILES:
COC(=O)c1ccc(cc1)C(=O)C#Cc1ccccc1