Target
GTPase KRas [1-37]
Ligand
BDBM54653
Substrate
n/a
Meas. Tech.
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54653
Synonyms:
4-[3-(2-methylphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | 4-[5-(o-tolyl)-3-phenyl-2-pyrazolin-1-yl]benzenesulfonamide | KUC103429N | UNM-0000306148 | cid_44143704
Type:
Small organic molecule
Emp. Form.:
C22H21N3O2S
Mol. Mass.:
391.486
SMILES:
Cc1ccccc1C1CC(=NN1c1ccc(cc1)S(N)(=O)=O)c1ccccc1 |c:10|
Structure:
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