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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54625
Substrate
n/a
Meas. Tech.
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54625
Synonyms:
3-(3,4-dimethoxyphenyl)-5-(4-fluorophenyl)-2-phenyl-3,4-dihydropyrazole | 5-(3,4-dimethoxyphenyl)-3-(4-fluorophenyl)-1-phenyl-2-pyrazoline | UNM-0000305864 | cid_2883145
Type:
Small organic molecule
Emp. Form.:
C23H21FN2O2
Mol. Mass.:
376.4234
SMILES:
COc1ccc(cc1OC)C1CC(=NN1c1ccccc1)c1ccc(F)cc1 |c:13|
Structure:
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