Target
GTPase KRas [1-37]
Ligand
BDBM54673
Substrate
n/a
Meas. Tech.
Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
EC50
30000±n/a nM
Citation
 PubChem, PC Pyrazoline SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54673
Synonyms:
4-[3-(2-bromophenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | 4-[5-(2-bromophenyl)-3-phenyl-2-pyrazolin-1-yl]benzenesulfonamide | KUC103480N | cid_44216862
Type:
Small organic molecule
Emp. Form.:
C21H18BrN3O2S
Mol. Mass.:
456.356
SMILES:
NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccccc1Br)c1ccccc1 |c:12|
Structure:
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