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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46206
Substrate
n/a
Meas. Tech.
MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50
129±n/a nM
Citation
 PubChem, PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46206
Synonyms:
MLS-0109562.0001 | [1-(2-phenoxyethyl)-3-indolyl]-(1-pyrrolidinyl)methanethione | [1-(2-phenoxyethyl)indol-3-yl]-pyrrolidin-1-yl-methanethione | [1-(2-phenoxyethyl)indol-3-yl]-pyrrolidin-1-ylmethanethione | [1-(2-phenoxyethyl)indol-3-yl]-pyrrolidino-methanethione | cid_1324805
Type:
Small organic molecule
Emp. Form.:
C21H22N2OS
Mol. Mass.:
350.477
SMILES:
S=C(N1CCCC1)c1cn(CCOc2ccccc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: