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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46249
Substrate
n/a
Meas. Tech.
MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50
2820±n/a nM
Citation
 PubChem, PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46249
Synonyms:
(4E)-4-[(cyclohexylamino)-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(cyclohexylamino)-mercaptomethylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[(cyclohexylamino)-sulfanyl-methylidene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[(cyclohexylamino)-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | MLS-0412117.0001 | cid_5504142
Type:
Small organic molecule
Emp. Form.:
C14H19NO2S
Mol. Mass.:
265.371
SMILES:
COc1cc(ccc1O)C(=S)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: