Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM46261
Substrate
n/a
Meas. Tech.
MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds
IC50
100000±n/a nM
Citation
 PubChem, PC MOA HePTP Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM46261
Synonyms:
1-(2-phenoxyethyl)-N-propan-2-yl-3-indolecarbothioamide | 1-(2-phenoxyethyl)-N-propan-2-yl-indole-3-carbothioamide | 1-(2-phenoxyethyl)-N-propan-2-ylindole-3-carbothioamide | MLS-0412136.0001 | N-isopropyl-1-(2-phenoxyethyl)indole-3-carbothioamide | cid_44182142
Type:
Small organic molecule
Emp. Form.:
C20H22N2OS
Mol. Mass.:
338.466
SMILES:
CC(C)NC(=S)c1cn(CCOc2ccccc2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: