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Target
Dual specificity protein phosphatase 3
Ligand
BDBM46286
Substrate
n/a
Meas. Tech.
MOA VHR1 Fluorescent secondary assay for identification of redox-state modulating compounds
IC50
220±n/a nM
Citation
 PubChem, PC MOA VHR1 Fluorescent secondary assay for identification of redox-state modulating compounds PubChem Bioassay (2009)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM46286
Synonyms:
(4E)-4-[[[4-fluoranyl-3-(trifluoromethyl)phenyl]methylamino]-sulfanyl-methylidene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[4-fluoro-3-(trifluoromethyl)benzyl]amino]-mercapto-methylene]-2-methoxy-cyclohexa-2,5-dien-1-one | (4E)-4-[[[4-fluoro-3-(trifluoromethyl)phenyl]methylamino]-mercaptomethylidene]-2-methoxy-1-cyclohexa-2,5-dienone | (4E)-4-[[[4-fluoro-3-(trifluoromethyl)phenyl]methylamino]-sulfanylmethylidene]-2-methoxycyclohexa-2,5-dien-1-one | MLS-0425623.0001 | cid_44229072
Type:
Small organic molecule
Emp. Form.:
C16H13F4NO2S
Mol. Mass.:
359.339
SMILES:
COc1cc(ccc1O)C(=S)NCc1ccc(F)c(c1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: