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Target
Bcl-2-related protein A1
Ligand
BDBM33101
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1
EC50
3000±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM33101
Synonyms:
1,5-diphenyl-1H-imidazole-2-thiol | 1,5-diphenyl-4-imidazoline-2-thione | 3,4-diphenyl-1H-imidazole-2-thione | MLS000575129 | SMR000196363 | cid_807871
Type:
Small organic molecule
Emp. Form.:
C15H12N2S
Mol. Mass.:
252.334
SMILES:
S=c1[nH]cc(-c2ccccc2)n1-c1ccccc1
Structure:
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