Target
Bcl-2-like protein 2
Ligand
BDBM33118
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
EC50
4700±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM33118
Synonyms:
2-[[(5Z)-4-keto-5-p-anisylidene-2-thiazolin-2-yl]thio]acetic acid ethyl ester | 2-[[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-2-thiazolyl]thio]acetic acid ethyl ester | MLS000560884 | SMR000174476 | [5-(4-Methoxy-benzylidene)-4-oxo-4,5-dihydro-thiazol-2-ylsulfanyl]-acetic acid ethyl ester | cid_5409636 | ethyl 2-[[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxidanylidene-1,3-thiazol-2-yl]sulfanyl]ethanoate | ethyl 2-[[(5Z)-5-[(4-methoxyphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]sulfanyl]acetate
Type:
Small organic molecule
Emp. Form.:
C15H15NO4S2
Mol. Mass.:
337.414
SMILES:
CCOC(=O)CSC1=NC(=O)\C(S1)=C\c1ccc(OC)cc1 |t:7|
Structure:
Search PDB for entries with ligand similarity: