Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM54769
Substrate
n/a
Meas. Tech.
HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies
IC50
4777±0 nM
Citation
 PubChem, PC HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies PubChem Bioassay (2009)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM54769
Synonyms:
4-({2-bromo-4-[(2,5-dioxo-4-imidazolidinylidene)methyl]-6-ethoxyphenoxy}methyl)benzoic acid | 4-[[2-bromo-4-[(E)-(2,5-diketoimidazolidin-4-ylidene)methyl]-6-ethoxy-phenoxy]methyl]benzoic acid | 4-[[2-bromo-4-[(E)-(2,5-dioxo-4-imidazolidinylidene)methyl]-6-ethoxyphenoxy]methyl]benzoic acid | 4-[[2-bromo-4-[(E)-(2,5-dioxoimidazolidin-4-ylidene)methyl]-6-ethoxyphenoxy]methyl]benzoic acid | 4-[[4-[(E)-[2,5-bis(oxidanylidene)imidazolidin-4-ylidene]methyl]-2-bromanyl-6-ethoxy-phenoxy]methyl]benzoic acid | MLS000690004 | SMR000298732 | cid_1334608
Type:
Small organic molecule
Emp. Form.:
C20H17BrN2O6
Mol. Mass.:
461.263
SMILES:
CCOc1cc(\C=C2\NC(=O)NC2=O)cc(Br)c1OCc1ccc(cc1)C(O)=O
Structure:
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