Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM54847
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
8380±1110 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54847
Synonyms:
2-(1-iminoisoindolin-2-yl)-2-phenyl-1-(p-tolyl)ethanone | 2-(1-iminoisoindolin-2-yl)-2-phenyl-1-(p-tolyl)ethanone;hydrobromide | 2-(3-azanylidene-1H-isoindol-2-yl)-1-(4-methylphenyl)-2-phenyl-ethanone | 2-(3-imino-1H-isoindol-2-yl)-1-(4-methylphenyl)-2-phenylethanone | BRD-A40632143-004-04-3 | cid_4131023
Type:
Small organic molecule
Emp. Form.:
C23H20N2O
Mol. Mass.:
340.4177
SMILES:
Cc1ccc(cc1)C(=O)C(N1Cc2ccccc2C1=N)c1ccccc1
Structure:
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