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Target
Streptokinase A
Ligand
BDBM54851
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
3966±1222 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54851
Synonyms:
3-(4-bromophenyl)-1-(4-hydroxybutylamino)-2-phenyl-3-nonanol | 3-(4-bromophenyl)-1-(4-hydroxybutylamino)-2-phenyl-nonan-3-ol | 3-(4-bromophenyl)-1-(4-hydroxybutylamino)-2-phenyl-nonan-3-ol;hydrochloride | 3-(4-bromophenyl)-1-(4-hydroxybutylamino)-2-phenylnonan-3-ol | 3-(4-bromophenyl)-1-(4-oxidanylbutylamino)-2-phenyl-nonan-3-ol | BRD-A91513005-001-01-2 | cid_16193797
Type:
Small organic molecule
Emp. Form.:
C25H36BrNO2
Mol. Mass.:
462.463
SMILES:
CCCCCCC(O)(C(CNCCCCO)c1ccccc1)c1ccc(Br)cc1
Structure:
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