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Target
Streptokinase A
Ligand
BDBM54855
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
24883±1369 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54855
Synonyms:
(4-benzhydrylpiperazin-1-yl)-(5-methoxy-3-methyl-1-benzofuran-2-yl)methanone | (4-benzhydrylpiperazino)-(5-methoxy-3-methyl-benzofuran-2-yl)methanone | BRD-K02370975-001-04-3 | [4-(diphenylmethyl)-1-piperazinyl]-(5-methoxy-3-methyl-2-benzofuranyl)methanone | [4-(diphenylmethyl)piperazin-1-yl]-(5-methoxy-3-methyl-1-benzofuran-2-yl)methanone | cid_24982824
Type:
Small organic molecule
Emp. Form.:
C28H28N2O3
Mol. Mass.:
440.5335
SMILES:
COc1ccc2oc(C(=O)N3CCN(CC3)C(c3ccccc3)c3ccccc3)c(C)c2c1
Structure:
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